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HBC

Catalog No.
A8786
For the production of fluorescent RNAs, used in live imaging of cellular RNAs.
Grouped product items
SizePriceStock Qty
1mg
$99.00
In stock
5mg
$129.00
In stock
10mg
$194.00
In stock
25mg
$388.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

HBC (HBC 530) is a synthetic dye similar to GFP fluorophores, featuring a structurally rigid electron acceptor and strong electron donor structure. HBC itself does not fluoresce in solution, but when it binds to Pepper (RNA aptamer), it forms a tight complex, activates and emits bright fluorescence, with a binding constant (Kd) of approximately 3.5 nM. The emission peaks of HBC vary in different Pepper complexes, covering a visible spectrum ranging from cyan to red. The typical excitation/emission wavelength of HBC 530 is 485/530 nm, which is highly suitable for biological imaging applications such as live cell imaging of RNA.

Chemical Properties

StorageStore at -20°C away from light for 3 years.
M.Wt303.36
Cas No.156840-13-0
FormulaC19H17N3O
Solubilityinsoluble in EtOH; insoluble in H2O; ≥21.2 mg/mL in DMSO
Chemical Name(E)-4-(1-cyano-2-(4-((2-hydroxyethyl)(methyl)amino)phenyl)vinyl)benzonitrile
SDFDownload SDF
Canonical SMILESOCCN(C)C1=CC=C(/C=C(C#N)\C2=CC=C(C#N)C=C2)C=C1
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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