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Glibenclamide

In stock
Catalog No.
B1296
Insulin production modulator
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
500mg
$48.00
In stock
1g
$66.00
In stock

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Background

Glibenclamide is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt494
Cas No.10238-21-8
FormulaC23H28ClN3O5S
Solubility≥49.4mg/mL in DMSO
Chemical Name5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
SDFDownload SDF
Canonical SMILESCOC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

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