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DR 2313

Catalog No.
PARP inhibitor
Grouped product items
SizePriceStock Qty
Ship with 5-10 days
Ship with 5-10 days
Ship with 5-10 days

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Competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro. Brain penetrant.

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at 4°C
Cas No.284028-90-6
Solubility≥83.3mg/mL in DMSO, ≥9.1mg/mL in H2O
Chemical Name2-methyl-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one
SDFDownload SDF
Canonical SMILESCC1=NC(=O)C2=C(N1)CCSC2
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Biological Activity

DR 2313 is a competitive inhibitor of PARP1 and PARP2 with IC50 of 0.20 and 0.24 μM respectively.
Targets PARPK1 PARP2        
IC50 0.20 μM 0.24 μM        

Quality Control

Quality Control & MSDS

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Chemical structure

DR 2313