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Cobimetinib (racemate)

Catalog No.
A3322
Selective MEK inhibitor
Grouped product items
SizePriceStock Qty
2mg
$150.00
Ship with 10-15 days
5mg
$225.00
Ship with 10-15 days
10mg
$420.00
Ship with 10-15 days
50mg
$1,050.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

GDC-0973(XL-518; GDC 0973) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors.

Chemical Properties

StorageStore at -20°C
M.Wt531.31
Cas No.934662-91-6
FormulaC21H21F3IN3O2
SynonymsGDC-0973 racemate;XL-518;GDC 0973;XL 518;GDC0973;XL518
SolubilitySoluble in DMSO
Chemical Name[3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-(3-hydroxy-3-piperidin-2-ylazetidin-1-yl)methanone
SDFDownload SDF
Canonical SMILESC1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Cobimetinib (racemate)