|Cobimetinib (R-enantiomer) Selective MEK inhibitor|
Sample solution is provided at 25 µL, 10mM.
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|Cas No.||934660-94-3||SDF||Download SDF|
|Synonyms||GDC-0973 R-enantiomer;XL-518 R-enantiomer|
|Solubility||Soluble in DMSO||Storage||Store at -20°C|
|Shipping Condition||Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|
GDC-0973(XL-518) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors.