Toggle Nav
  • Menu
  • Setting

Cobimetinib (R-enantiomer)

Catalog No.
Selective MEK inhibitor
Grouped product items
SizePriceStock Qty
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors


GDC-0973(XL-518) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors.

Chemical Properties

StorageStore at -20°C
Cas No.934660-94-3
SynonymsGDC-0973 R-enantiomer;XL-518 R-enantiomer
SolubilitySoluble in DMSO
Chemical Name[3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl]methanone
SDFDownload SDF
Canonical SMILESC1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Cobimetinib (R-enantiomer)