Ac-IEPD-AFC|Recognition motif for serine protease granzyme B|CAS# 1135417-31-0

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Ac-IEPD-AFC Recognition motif for serine protease granzyme B

Catalog No.A4418

Size	Price	Stock	Qty
5mg	$237.00	In stock

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Sample solution is provided at 25 µL, 10mM.

Publications citing ApexBio Products

Nature.
2017 Jan 19;541(7637):417-420.

Nature.
2018 Nov;563(7731):407-411.

Nature.
2018 Jun 13.

Nature.
2018 Jun 27.

Nature.
2018 Mar 29;555(7698):673-677.

Nature.
2017 Sep 7;549(7670):96-100.

Nature.
2016 Apr 21;532(7599):398-401.

Science.
2016 Aug 5;353(6299)594-8

Nat Nanotechnol.
2017 Dec;12(12):1190-1198.

Nature Biotechnology.
2017 Jun;35(6):569-576

Nat Med.
2018 Sep 17.

Cell.
2018 Dec 21. pii: S0092-8674(18)31561-7.

Cell.
Available online 25 October 2018.

Cell.
2018 Sep 27. pii: S0092-8674(18)31183-8.

Cell.
2018 Jun 28;174(1):172-186.e21.

Cell.
2018 Feb 22;172(5):1007-1021.e17.

Cell.
2017 Nov 30;171(6):1284-1300.e21.

Cell.
2017 Aug 17. pii: S0092-8674(17)30869-3.

Cell.
2017 Jul 13;170(2):312-323

Nat Med.
2018 Jan 29.

Nat Med.
2017 Nov;23(11):1342-1351.

Cell.
2017 Apr 6;169(2):286-300.

Cell.
2015 Aug 27;162(5):987-1002.

Cell.
2015 Feb 12;160(4):729-44.

Nature Medicine.
2017 Apr;23(4):493-500.

Cancer Cell.
2018 May 14;33(5):905-921.e5.

Cancer Cell.
2018 Apr 9;33(4):752-769.e8.

Cancer Cell.
2018 Mar 12;33(3):401-416.e8.

Cancer Cell.
2017 Aug 14;32(2):253-267.e5.

Nat Methods.
2018 Jul;15(7):523-526.

Cell Stem Cell.
2018 May 3;22(5):769-778.e4.

Cell Stem Cell.
2017 Nov 20. pii: S1934-5909(17)30375-2.

Quality Control

Quality Control & MSDS

View current batch:

Purity = 98.00%

Chemical structure

Ac-IEPD-AFC

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Chemical Properties

Cas No.	1135417-31-0	SDF	Download SDF
Chemical Name	4-[(2-acetamido-3-methylpentanoyl)amino]-5-[2-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid
Canonical SMILES	CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C(F)(F)F)NC(=O)C
Formula	C₃₂H₃₈F₃N₅O₁₁	M.Wt	725.67
Solubility	Soluble to 14.51 mg/ml in DMSO	Storage	Desiccate at -20°C
Shipping Condition	Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Peptide sequence shown to be preferred recognition motif for the serine protease granzyme B. Fluorogenic substrate.