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corticosteroid and anti-inflammatory
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6α-Methyl-11β-hydroxyprogesterone is a synthetic glucocorticoid which has been used in the treatment of inflammatory eye diseases. 6α-Methyl-11β-hydroxyprogesterone is a corticosteroid with anti-inflammatory properties which has been discontinued in the United States. The structure of 6α-Methyl-11β-hydroxyprogesterone is very similar to progesterone. Neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone [1, 2].

[1] The dictionary of drugs: chemical data: chemical data, structures and bibliographies[M].  Springer, 2014.
[2] SPAETH G L.  Hydroxymethylprogesterone: An anti-inflammatory steroid without apparent effect on intraocular pressure[J]. Archives of Ophthalmology, 1966, 75(6): 783-787.

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at -20°C
Cas No.2668-66-8
SynonymsNSC 63278,Visudrisone
Solubility≤1mg/ml in ethanol;1mg/ml in methanol;1mg/ml in acetonitrile
Chemical Name(6α,11β)-11-hydroxy-6-methyl-pregn-4-ene-3,20-dione
SDFDownload SDF
Canonical SMILESC[[email protected]@]12[[email protected]](CC[[email protected]@H]2C(C)=O)([H])[[email protected]]3([H])C[[email protected]](C)C4=CC(CC[[email protected]]4(C)[[email protected]@]3([H])[[email protected]@H](O)C1)=O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure