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Signaling Pathways

Items 61-69 of 69

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  1. (-)-Huperzine A
    A1932 (-)-Huperzine A
    Target: NMDA Receptors|AChE
    Summary: NMDA receptor antagonist/AChE inhibitor
      insoluble in H2O; ≥12.12 mg/mL
  2. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  3. BAY 61-3606
    A3227 BAY 61-3606
    Target: Syk
    Summary: Syk Inhibitor
      insoluble in H2O; insoluble in EtOH; ≥7.94 mg/mL
  4. Bivalirudin Trifluoroacetate
    A3244 Bivalirudin Trifluoroacetate
    Target: thrombin
    Summary: Reversible thrombin inhibitor
      ≥54.5 mg/mL
  5. Cathepsin S inhibitor
    A3284 Cathepsin S inhibitor
     1 Citation
    Target: Cathepsins
    Summary: Blocks MHCII antigen presentation
      ≥24.25 mg/mL
  6. CVT-313
    A3336 CVT-313
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Cdk2 inhibitor
      ≥20 mg/mL
  7. ML-7 hydrochloride
    A3626 ML-7 hydrochloride
    Target: Myosin light chain kinases (MLCKs)
    Summary: Myosin light chain kinase inhibitor
      insoluble in EtOH; ≥15.95 mg/mL
  8. Otamixaban
    A3690 Otamixaban
    Target: Factor Xa
    Summary: Direct factor Xa inhibitors,potent and selective
      ≥22.35 mg/mL
  9. SCH 527123
    A3802 SCH 527123
     5 Citation
    Target: CXCR
    Summary: CXCR1 and CXCR2 receptors antagonist

Items 61-69 of 69

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Category
  1. Proteases14item
  2. Apoptosis1 item
  3. Chromatin/Epigenetics7item
  4. Metabolism1 item
  5. MAPK Signaling5item
  6. Tyrosine Kinase9item
  7. DNA Damage/DNA Repair4item
  8. PI3K/Akt/mTOR Signaling4item
  9. Cell Cycle/Checkpoint9item
  10. Ubiquitination/ Proteasome8item
  11. JAK/STAT Signaling3item
  12. TGF-β / Smad Signaling3item
  13. GPCR/G protein2item
  14. Stem Cell2item
  15. Membrane Transporter/Ion Channel5item
  16. Endocrinology and Hormones1 item
  17. Neuroscience3item
  18. Others2item
  19. Immunology/Inflammation1 item
Specificity
  1. Selective56item
  2. Non-Selective1 item
Target
  1. Caspases1 item
  2. Cyclin-Dependent Kinases2item
  3. Proteasome3item
  4. Cathepsins4item
  5. Histone Deacetylases (HDACs)2item
  6. Akt1 item
  7. PI3K2item
  8. CXCR1 item
  9. Raf1 item
  10. Aurora Kinases2item
  11. mTOR1 item
  12. MMP1 item
  13. Myosin II ATPases1 item
  14. Factor Xa1 item
  15. LPA Receptors1 item
  16. PLK1 item
  17. Chk1 item
  18. VEGFR1 item
  19. JNK1 item
  20. MEK1 item
  21. Deubiquitinating enzymes (DUBs)1 item
  22. Src1 item
  23. NMDA Receptors1 item
  24. Microtubules/Tubulins2item
  25. EGFR2item
  26. FAK3item
  27. JAK2item
  28. Syk1 item
  29. AMPK1 item
  30. S-nitrosoglutathione reductase1 item
  31. CFTR1 item
  32. thrombin1 item
  33. ErbB2item
  34. Actin1 item
  35. ERK1 item
  36. PKC1 item
  37. Calpains1 item
  38. M1 Receptors1 item
  39. SMYD21 item
  40. RAD511 item
  41. Trypsins1 item
  42. Pyk23item
  43. Voltage-gated Calcium Channels (CaV)1 item
  44. Insulin and Insulin-like Receptors1 item
  45. ALK1 item
  46. GTPases1 item
  47. CETP1 item
  48. PKA1 item
  49. Myosin light chain kinases (MLCKs)1 item
  50. MK21 item
  51. ATM/ATR1 item
  52. AChE1 item
  53. ZAP-701 item
  54. Catechol O-Methyltransferase (COMT)1 item
  55. DPP-41 item
  56. Dipeptidyl-peptidase II1 item
  57. P97 ATPase1 item
  58. Aromatases1 item
  59. UCH1 item
  60. MST1 item
  61. ATM1 item
Reported Experiments
  1. Animal Experiments58item
  2. Cell Experiments37item
Related Disease
  1. Acute Myelogenous Leukemia1 item
  2. Acute Myeloid Leukemia1 item
  3. Breast Cancer10item
  4. Cancer30item
  5. Colon Cancer3item
  6. Colorectal Cancer2item
  7. Diabetes1 item
  8. Glioblastoma1 item
  9. Glioma1 item
  10. Hepatocellular Carcinoma2item
  11. Hypercholesterolemia1 item
  12. Inflammatory Diseases2item
  13. Leukemia2item
  14. Lung Cancer2item
  15. Lymphoma1 item
  16. Mantle Cell Lymphoma1 item
  17. Multiple Myeloma1 item
  18. Pancreatic Cancer4item
  19. Prostate Cancer1 item
  20. Psoriasis1 item
  21. Renal Cancer2item
  22. Rheumatoid Arthritis1 item