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Amiodarone HCl

Catalog No.
Anti-arrhythmic drug
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
In stock
In stock
Ship with 10-15 days

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Amiodarone HCl is an anti-arrhythmic drug [1].

Amiodarone HCl has shown a non-competitive inhibition of the chronotropic effect of isoproterenol with a pD’ value of ~4.17. In addition, Amiodarone HCl has been reported to inhibit the norepinephrine-induced contractions in a non-competitive type with a pD’ value of about 4.06. Besides, all the results have been suggested that Amiodarone HCl does not compete with the agonists at their respective recognition sites. Amiodarone HCl has been found to be a different antagonizes types of anonists: β1-adrenergic agonists like isoproterenol, α-adrenergic agonists like norepinephrine and glucagon. Apart from these, Amiodarone HCl has exhibited tissular specificity. The adrenergic (glucagon) antagonism has been shown only on the heart and the arteries. Amiodarone HCl has noted no cpinephrine-induced lipolysis of the epididymal fat pad [1].

[1] Polster P, Broekhuysen J. The adrenergic antagonism of amiodarone. Biochem Pharmacol. 1976 Jan 15;25(2):131-4.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
Cas No.19774-82-4
Solubilityinsoluble in H2O; ≥13.8 mg/mL in DMSO with gentle warming; ≥3.36 mg/mL in EtOH with ultrasonic
Chemical Name(2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone;hydrochloride
SDFDownload SDF
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Chemical structure

Amiodarone HCl