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1,2,3,4,5,6-Hexabromocyclohexane

In stock
Catalog No.
A4510
JAK2 tyrosine kinase inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
50mg
$106.00
In stock

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Background

Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.

Chemical Properties

Physical AppearanceA solid
StorageStore at RT
M.Wt557.54
Cas No.1837-91-8
FormulaC6H6Br6
Solubility≥8.2mg/mL in DMSO with gentle warming, <2.36 mg/mL in EtOH, <2.57 mg/mL in H2O
Chemical Name1,2,3,4,5,6-hexabromocyclohexane
SDFDownload SDF
Canonical SMILESC1(C(C(C(C(C1Br)Br)Br)Br)Br)Br
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

1,2,3,4,5,6-Hexabromocyclohexane