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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B1523 PF-573228
4 Citation

Summary: ATP-competitive FAK inhibitor

insoluble in EtOH; insoluble in H2O; ≥166.6 mg/mL
B1343 Phenoxybenzamine HCl

Summary: Adrenergic receptor antagonist

insoluble in H2O; ≥17.02 mg/mL
B1409 Benidipine HCl

Summary: Calcium channel blocker

≥21.8 mg/mL
A8720 MYK-461

Summary: inhibits adenosine triphosphatase activity
A8764 Rapalink-1
5 Citation

Target: mTOR

Summary: third-generation mTOR inhibitor

≥178.4 mg/mL
A8779 WM-8014

Summary: Inhibitor for KAT6A (MOZ) and KAT6B (MORF/QKF), anticancer

insoluble in H2O; insoluble in EtOH; ≥76.1 mg/mL
B2284 Fostamatinib (R788)
1 Citation

Target: Syk

Summary: Spleen tyrosine kinase (Syk) inhibitor

insoluble in H2O; ≥100.4 mg/mL
B2303 Apatinib
4 Citation

Summary: VEGFR2 inhibitor, orally bioavailable, selective

≥49.4 mg/mL
B2296 Topotecan HCl
2 Citation

Summary: Topoisomerase 1 inhibitor

≥22.9 mg/mL
B2117 Pioglitazone
1 Citation

Summary: PPAR agonist

insoluble in H2O; insoluble in EtOH; ≥14.3 mg/mL