Signaling pathways
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BA4535 L2H2-6OTDSummary: L2H2-6OTD, containing one to four G-quadruplex binding loops, is a telomere inhibitor analog. - BA4536 BisantreneSummary: Bisantrene is a potent anticancer agent that exerts cytotoxicity by affecting DNA insertion.
- BA4537 MerbaroneSummary: Merbarone (NSC336628) is an orally active topoisomerase II inhibitor.
- BA4538 IndotecanSummary: Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent topoisomerase I inhibitor.
- BA4539 IntoplicineSummary: Intoplicine (RP60475), an antitumor derivative of the 7H benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase and inhibitor.
- BA4540 GimatecanSummary: Gimatecan (ST1481) is a potent topoisomerase I inhibitor.
- BA4541 LurtotecanSummary: Lurtotecan (GI147211; OSI-211) is a semi-synthetic camptothecin analog that is a topoisomerase I inhibitor.
- BA4542 RubitecanSummary: Rubitecan (RFS2000), a camptothecin derivative, is an orally active inhibitor with broad antitumor activity.
- BA4543 IsosteviolSummary: Isosteviol ((-)-Isosteviol) is a steviol glycoside derivative that is produced by acid-catalyzed hydrolysis of steviol glycosides.
- BA4544 GroenlandicineSummary: Groenlandicine is a proto-berberine alkaloid isolated from Rhizoma Coptidis.