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CYP3A/CYP450

CYP3A4 is an enzyme of cytochrome P450 superfamily found in human liver. It catalyzes the metabolism of endogenous and exogenous agents ( e.g. xenobiotics).

Items 1-10 of 17

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  1. 6,7-dihydroxy Bergamottin
    C4880 6,7-dihydroxy Bergamottin
    Summary: potent inhibitor of CYP3A4
      ≤10 mg/mL
  2. 4-phenyl-1,2,3-Thiadiazole
    C4691 4-phenyl-1,2,3-Thiadiazole
    Summary: selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1)
      ≤10 mg/mL
  3. DDMS
    C5228 DDMS
    Summary: CYP4A2 enzyme inhibitor
      ≤20 mg/mL
  4. PPOH
    C5234 PPOH
    Summary: inhibitor of CYP epoxidase activity on arachadonic acid
      ≤100 mg/mL
  5. 4β-hydroxy Cholesterol
    C5540 4β-hydroxy Cholesterol
    Summary: marker for CYP3A4/5 activity
      ≤20 mg/mL
  6. ABT
    B7737 ABT
    Summary: Cytochrome P450 inhibitor
      ≥12.93 mg/mL
  7. Methoxyresorufin
    B5723 Methoxyresorufin
    Summary: fluorometric substrate of cytochrome P450
      insoluble in DMSO
  8. Pentoxyresorufin
    B5724 Pentoxyresorufin
    Summary: fluorometric cytochrome P450 substrate
      insoluble in ethanol;insoluble in DMSO
  9. TMS
    B6768 TMS
    Summary: cytochrome P450 1B1 inhibitor
      Soluble in DMSO
  10. 3-Cyano-7-ethoxycoumarin
    B7714 3-Cyano-7-ethoxycoumarin
    Summary: Fluorescent P450 substrate
      Soluble in DMSO

Items 1-10 of 17

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