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DiscoveryProbe™ Neuroscience-related Compounds Panel

Catalog No.L1015
Size Price Stock Qty
In stock

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Sample solution is provided at 25 µL, 10mM.

Click and Customize the Panel with your own choices of compounds/size/quantities/chemical forms etc.

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Featured Products of the Panel

Catalog No. Product Name Summary Targets CAS Number Smiles
A2098 PRX-08066 Maleic acid 5-HT2B receptor antagonist,potent and selective Neuroscience|5-HT Receptor 866206-55-5 FC(C=C1)=C(C#N)C=C1CN(CC2)CCC2NC3=C(C=C(Cl)S4)C4=NC=N3.O=C(O)/C=C\C(O)=O
A8369 Atropine MAChRs antagonist Neuroscience|AChR 5908-99-6 CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O
A1664 Celecoxib Selective cyclooxygenase-2 (COX-2) inhibitor Neuroscience|COX 169590-42-5 CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
A3733 Pramipexole dihydrochloride Dopamine receptor agonist Neuroscience|Dopamine Receptor 104632-25-9 CCCNC1CCC2=C(C1)SC(=N2)N.Cl.Cl
A2700 10Panx Panx-1 mimetic inhibitor Neuroscience|Gap Junction 955091-53-9 CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=CNC4=CC=CC=C43)N
A2623 VU 0364439 Positive allosteric mGluR-4 modulator Neuroscience|GluR 1246086-78-1 C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl
Download the Neuroscience-related Compounds Panel - XLSX       Download the Neuroscience-related Compounds Panel - SDF

Signaling Pathway

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  • Available in stock with overnight delivery and free shipping over $500
  • Cost-effective and competitive price to save your findings
  • Potent, selective and cell-permeable in inhibiting or activating target molecules
  • Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
  • Detailed files describing potency, selectivity and applications etc.
  • Supported by published data from top peer-reviewed journals
  • Guaranteed high quality with NMR and HPLC validation

Storage and Shipping Information

Solubility Soluble in DMSO Storage Desiccate at -20°C
Packaging 96 well plate Form Powder
General tips For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request


A wide range of well-characterized bioactive molecules that covers various targets related to neuroscience, including 5-HT Receptor, Amyloid β, GABA and COX etc. Facilitate your research towards the insights of Alzheimer disease, Parkinson's disease and epilepsy etc. Applicable in cellular assays, animal models and drug screenings etc.


1. Noda M, Higashida H, Aoki S, Wada K. Multiple signal transduction pathways mediated by 5-HT receptors. Mol Neurobiol. 2004 Feb;29(1):31-9.
5-HT5A receptors are probably the least well understood among the 5-HT receptors, but the authors found that 5-HT5A receptors couple to multiple signaling cascades. When the 5-HT5A receptors were expressed in undifferentiated C6 glioma cells, they modulated the level of second messengers. The author results indicate that 5-HT5A receptors couple to multiple second messenger systems and may contribute to the complicated physiological and pathophysiological states.