Phosphatase Inhibitor Cocktail 1 (100X in DMSO)
Catalog No.
K1012
A ready-to-use 100X phosphatase inhibitor cocktail concentrate (dissolved in DMSO) for inhibiting serine/threonine protein phosphatases and alkaline phosphatase isoenzymes.
Featured Products
Many cellular processes are regulated by reversible phosphorylation of proteins, and approximately 30% of proteins may become phosphorylated during their lifetime. Cellular crude extracts contain numerous endogenous enzymes, such as phosphatases and proteases, which can degrade and modify proteins present in the extract. Addition of inhibitors for these enzymes is the optimal approach for maximizing intact protein yield.
Phosphatase Inhibitor Cocktail 1 inhibits alkaline phosphatase L-isoenzymes and serine/threonine phosphatases, such as protein phosphatases 1 and 2A (PP1 and PP2A). It has been optimized and tested in cell extracts from various animal tissues.This Phosphatase Inhibitor Cocktail 1 contains Cantharidin, Bromotetramisole, and Microcystin LR. It is supplied as a ready-to-use solution in DMSO.
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Thaw at room temperature, add at 1:100 (v/v) dilution to solution samples (such as cell lysates or tissue extracts) before assaying.
Applications: WB, Co-IP, pull-down, IF, IHC, kinase assay and etc.
| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
| N1686 | Cantharidin | Inhibitor of protein phosphatases 1/2A | Natural Products | 56-25-7 | O=C([C@@]1(C([H])([H])[H])[C@]2(C([H])([H])[H])[C@@]3([H])O[C@]1([H])C([H])([H])C3([H])[H])OC2=O |
| B4750 | (-)-p-Bromotetramisole Oxalate | ALP inhibitor, potent and non-specific | Others|Others | 62284-79-1 | BrC(C=C1)=CC=C1[C@H]2N=C3SCCN3C2.OC(C(O)=O)=O |
| B3698 | Microcystin-LR | Inhibitor of protein phosphatase PP1/PP2A,potent and selective | Chromatin/Epigenetics|Protein Ser/Thr Phosphatases | 101043-37-2 | CC1C(NC(=O)C(NC(=O)C(C(NC(=O)C(NC(=O)C(NC(=O)C(=C)N(C(=O)CCC(NC1=O)C(=O)O)C)C)CC(C)C)C(=O)O)C)CCCN=C(N)N)C=CC(=CC(C)C(CC2=CC=CC=C2)OC)C |
| Stored at -20°C, and stable for at least 12 months. When kept at 2-8°C, the product remains stable for 2 months. | |||||
Stored at -20°C, and stable for at least 12 months. When kept at 2-8°C, the product remains stable for 2 months.
