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2'-O-Methyl-2-Amino-ATP

Catalog No.
B7992
Modified nucleoside triphosphate with methylation at the 2'-hydroxyl group and an amino substitution at the 2-position of the adenine ring, used for RNA stability studies.
Grouped product items
SizePriceStock Qty
10ul (100 mM)
$158.00
Please inquire
50ul (100 mM)
$666.00
Please inquire
100ul (100 mM)
$1,128.00
Please inquire
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

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Description

2'-O-Methyl-2-Amino-ATP is a modified nucleoside triphosphate wherein the 2'-hydroxyl group on adenosine is methylated, and the adenine ring carries an amino substitution at the 2-position. This dual modification significantly alters the nucleotide's chemical properties and biological functionalities. 2'-O-Methyl-2-Amino-ATP can be incorporated into RNA molecules during in vitro transcription reactions, producing RNAs containing this modification. The methylation enhances RNA stability by reducing susceptibility to exonuclease degradation, facilitating the study of RNA functions in both in vitro and in vivo experiments. Furthermore, the amino modification can influence RNA secondary structure and its interactions with proteins, making it particularly valuable for studying RNA-protein interactions as well as RNA modifications and functions.

Chemical Properties

Physical AppearanceSolution
StorageStore at -20°C or below
M.Wt536.2 (free acid)
FormulaC11H19N6O13P3 (free acid)
Synonyms2'-O-Methyl-2-aminoadenosine-5'-Triphosphate, 2'-O-Methyl-2,6-Diaminopurine-ribose-5'-Triphosphate, 2'-O-Methyl-DAP-rTP
Chemical Namelithium (5-(2,6-diamino-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl triphosphate
SDFDownload SDF
Canonical SMILESNC1=NC(N)=NC2=C1N=CN2C3C(OC)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O3.[Li+].[Li+].[Li+].[Li+]
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

2