5-hme-CTP
Catalog No.
B8055
5-Hydroxymethyl-modified cytidine triphosphate for mRNA in vitro transcription synthesis
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5-hme-CTP (5-hydroxymethylcytidine triphosphate) is a modified cytidine triphosphate bearing a hydroxymethyl group at the 5-position carbon. This modification can enhance RNA stability and functionality. During in vitro mRNA synthesis, 5-hme-CTP can be incorporated into RNA molecules, producing RNA containing 5-hydroxymethylcytidine. Hydroxymethyl-modified RNA plays an essential role in studying RNA structure, function, and RNA-protein interactions. Additionally, 5-hme-CTP significantly improves RNA stability by reducing its intracellular degradation. Thus, this modified nucleotide has broad applications in gene expression research, RNA-based drug development, and gene therapy.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 513.1 |
| Formula | C10H18N3O15P3 (free acid) |
| Synonyms | 5-Hydroxymethylcytidine-5’-Triphosphate, 5-hm-CTP, 5-HmCTP, 5-Hydroxymethyl-CTP |
| Chemical Name | lithium (5-(4-amino-5-(hydroxymethyl)-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | NC(C(CO)=CN1C2C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)=NC1=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity ≥95% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
