N6-Methyl-ATP
Catalog No.
B7966
Methylated adenosine triphosphate (m6A) for in vitro transcription-based mRNA synthesis
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N6-Methyl-ATP (m6ATP) is a base-modified analogue of adenosine and is a minor nucleotide found in natural RNA. It is commonly present in messenger RNA (mRNA) of eukaryotes, and plays a crucial regulatory role in RNA splicing, export, stability, and translation processes. N6-Methyl-ATP can serve as a substrate for in vitro RNA polymerase, and is used as a complete substitute for ATP in mRNA modification reactions. Additionally, studies have shown that N6-Methyl-ATP has an effective agonist effect on P2Y phosphoreceptors in guinea pigs and Escherichia coli.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 521.2 (free acid) |
| Formula | C11H18N5O13P3 (free acid) |
| Synonyms | N6-Methyladenosine-5'-Triphosphate |
| Chemical Name | lithium (3,4-dihydroxy-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | OC1C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)OC(N2C=NC3=C2N=CN=C3NC)C1O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = 98.02% by AX-HPLC
- COA (Certificate Of Analysis)
- HPLC
- MS (Mass Spectrometry)
- MSDS (Material Safety Data Sheet)
Chemical structure
