RP-6685
Catalog No.
BA3963
RP-6685 is a potent and selective and orally active DNA polymerase theta inhibitor.
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RP-6685 is a potent and selective and orally active DNA polymerase theta inhibitor with a value of 5.8 nM (PicoGreen assay).RP-6685 exhibits antitumor effects in a mouse tumor transplantation model.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 497.37 |
| Cas No. | 2832047-80-8 |
| Formula | C22H14F7N5O |
| Solubility | ≥51.2 mg/mL in DMSO; ≥7.53 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | N-(3-(6-aminopyridazin-3-yl)prop-2-yn-1-yl)-2-(3,5-bis(trifluoromethyl)pyridin-2-yl)-N-(4-fluorophenyl)acetamide |
| Canonical SMILES | O=C(N(CC#CC1=NN=C(N)C=C1)C2=CC=C(F)C=C2)CC3=NC=C(C(F)(F)F)C=C3C(F)(F)F |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
