Ivermectin
Catalog No.
A2813
NAChR/purinergic P2X4 receptor modulator
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Ivermectin is an FDA-approved broad-spectrum anti-parasitic medication used in humans to treat specific conditions like river blindness (onchocerciasis) and strongyloidiasis (threadworm infection), and topically for head lice and rosacea. It works by paralyzing and killing parasites.
- 1. Xiaoqian Tan, Yinling He, et al. "The dual role of FSP1 in programmed cell death: resisting ferroptosis in the cell membrane and promoting necroptosis in the nucleus of THP-1 cells." Mol Med. 2024 Jul 15;30(1):102 PMID: 39009982
- 2. Bikash Dangi, Nadezhda Y Davydova, et al. "Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4." Arch Biochem Biophys. 2020 Nov 13;108677. PMID: 33197431
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 875.09 |
| Cas No. | 70288-86-7 |
| Formula | C48H74O14 |
| Solubility | ≥43.75 mg/mL in DMSO; insoluble in H2O; ≥19.8 mg/mL in EtOH |
| Chemical Name | Ro 5-2807 |
| SDF | Download SDF |
| Canonical SMILES | C/C([C@@H](O[C@H]1C[C@H](OC)[C@@H](O[C@H]2C[C@H](OC)[C@@H](O)[C@H](C)O2)[C@H](C)O1)[C@@H](C)/C=C/C=C(CO3)/[C@@]([C@@]3([H])[C@H](O)C(C)=C4)(O)[C@@H]4C5=O)=C\C[C@@H]6C[C@H](O5)C[C@@]7(O[C@@]([C@@H](C)CC)([H])[C@@H](C)CC7)O6 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
