Biotin-11-dUTP
Catalog No.
B8336
A biotin-labeled dUTP
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Biotin-11-dUTP (CAS 1221498-88-9) is a biotin-conjugated analogue of deoxythymidine triphosphate (dTTP) that can be incorporated enzymatically into DNA or cDNA sequences during polymerase reactions. After integration, labeled nucleic acid fragments can be detected using streptavidin coupled to horseradish peroxidase (HRP), alkaline phosphatase (AP), fluorescent molecules, or bead-based capture systems. This approach is frequently utilized in polymerase chain reaction (PCR), nick translation, reverse transcription assays, and apoptosis studies, facilitating DNA probe labeling and molecular analysis workflows.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 887.44 |
| Cas No. | 1221498-88-9 |
| Formula | C28H44Li4N7O16P3S |
| Solubility | ≥100.7 mg/mL in H2O; ≥46.3 mg/mL in EtOH; ≥95.6 mg/mL in DMSO |
| Chemical Name | lithium (5-(4-amino-2-oxo-5-((E)-3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-en-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | O=C1N[C@]2([H])[C@]([C@H](CCCCC(NCCCCCC(NC/C=C/C3=CN(C(NC3N)=O)C4OC(COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)C(C4)O)=O)=O)SC2)([H])N1.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = 99.89% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
