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Tetracycline

Catalog No.
C6589
 
Grouped product items
SizePriceStock Qty
200mg
$50.00
In stock
1g
$85.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Tetracycline (CAS 60-54-8) is a broad-spectrum polyketide antibiotic originally isolated from Streptomyces species. It functions primarily through reversible binding to the bacterial 30S ribosomal subunit, disrupting the interaction of aminoacyl-tRNA with the ribosomal acceptor site and thereby inhibiting bacterial protein synthesis. Additionally, tetracycline interacts partially with the 50S ribosomal subunit and may compromise bacterial membrane integrity, causing leakage of intracellular components. Tetracycline remains widely employed in microbiological research as an antibiotic selection marker and a tool for investigating ribosomal functions.

Chemical Properties

StorageStore at -20°C
M.Wt444.43
Cas No.60-54-8
FormulaC22H24N2O8
Solubility≥74.9 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
Chemical Name(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
SDFDownload SDF
Canonical SMILESO=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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