Tetracycline
Catalog No.
C6589
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Tetracycline (CAS 60-54-8) is a broad-spectrum polyketide antibiotic originally isolated from Streptomyces species. It functions primarily through reversible binding to the bacterial 30S ribosomal subunit, disrupting the interaction of aminoacyl-tRNA with the ribosomal acceptor site and thereby inhibiting bacterial protein synthesis. Additionally, tetracycline interacts partially with the 50S ribosomal subunit and may compromise bacterial membrane integrity, causing leakage of intracellular components. Tetracycline remains widely employed in microbiological research as an antibiotic selection marker and a tool for investigating ribosomal functions.
| Storage | Store at -20°C |
| M.Wt | 444.43 |
| Cas No. | 60-54-8 |
| Formula | C22H24N2O8 |
| Solubility | ≥74.9 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| Chemical Name | (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
| SDF | Download SDF |
| Canonical SMILES | O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
