2-Thio-dTTP
Catalog No.
B8100
2-Thio-dTTP is a modified nucleotide analog, which is commonly used in molecular biology research.
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2-Thio-dTTP (2-thio-2'-deoxythymidine-5'-triphosphate) is a modified nucleotide analog in which the 2-position oxygen atom of thymine is substituted by sulfur. Incorporation of this modified nucleotide during DNA synthesis can influence DNA-protein interactions and alter nucleic acid stability. It is commonly utilized in molecular biology studies involving DNA replication fidelity, mutagenesis, and structural analyses of nucleic acids. Due to the sulfur substitution, 2-Thio-dTTP finds applications in biochemical assays and DNA sequencing methodologies.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 498.23 (free acid) |
| Formula | C10H17N2O13P3S (free acid) |
| Synonyms | 2-Thio-2'-deoxythymidine-5'-triphosphate |
| Chemical Name | lithium (3-hydroxy-5-(5-methyl-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | O=C(C(C)=CN1C2CC(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)NC1=S.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |