Toggle Nav
Close
  • Menu
  • Setting

Cy3 NHS ester

Catalog No.
A8107
Labeling of amino-groups in biomolecules.
Grouped product items
SizePriceStock Qty
5mg
$238.00
In stock
25mg
$790.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Sulfo-Cy3 NHS ester is a sulfonated, hydrophilic and highly water soluble dye. For labeling proteins and peptides, no organic co-solvent is needed. Sulfo-Cy3 NHS ester is ideal for proteins with low solubility and proteins prone to denaturation. Non-sulfonated Cy3 NHS ester is also available. In life science, the sulfonate groups make the Cy dyes soluble in water and also reduce fluorescence-quenching which can arise from dye–dye interactions.

In vitro, sulfo-Cy3 NHS ester can react with green-emitting QDs ligand-exchanged and LA/His-PIMA-PEG-NH2 to provide QD-dye conjugates [1].

Reference:
[1] Reid, D. A.; Keegan, S.; Leo-Macias, A.; Watanabe, G.; Strande, N.T.; Chang, H.H.; Oksuz, B.A.; Fenyo, D.; Lieber, M.R.; Ramsden, D.A.; Rothenberg, E. Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(20).

Product Citation

Chemical Properties

Storage 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
M.Wt727.84
Cas No.146368-16-3
FormulaC35H41N3O10S2
Solubilityinsoluble in EtOH; insoluble in DMSO; insoluble in H2O
Chemical Name2-((E)-3-((E)-1-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)prop-1-en-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
SDFDownload SDF
Canonical SMILESO=C(ON1C(CCC1=O)=O)CCCCCN(C(C=CC(S(=O)(O)=O)=C2)=C2C/3(C)C)C3=C\C=C\C4=[N+](CC)C(C=CC(S(=O)([O-])=O)=C5)=C5C4(C)CC)C)C)C
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Spectral properties

Excitation max (nm) 563 Emission max (nm) 584
Extinction Coefficient (M-1cm-1) 162000 Quantum Yield 0.1
CF260 0.03 CF280 0.06

Quality Control

Chemical structure

Cy3 NHS ester

Related Biological Data

Cy3 NHS ester

Related Biological Data

Cy3 NHS ester