Polyphyllin D
Catalog No.
N1925
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Polyphyllin D (CAS 55916-51-3) is a bioactive steroidal saponin isolated from the plant Paris yunnanensis Franch. It exhibits significant anticancer activity primarily through induction of apoptosis, cell-cycle arrest, and inhibition of cell migration and invasion. Studies suggest Polyphyllin D mediates its effects via modulation of signaling pathways including PI3K/Akt, NF-κB, and MAPK cascades. Due to these mechanistic insights, Polyphyllin D serves as a valuable research tool for investigating molecular pathways associated with tumorigenesis and metastatic progression.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 738.9 |
| Cas No. | 55916-51-3 |
| Formula | C39H62O13 |
| Synonyms | Chonglou saponin VI |
| Solubility | ≥73.9 mg/mL in EtOH with gentle warming; insoluble in H2O; ≥51.3 mg/mL in DMSO |
| Chemical Name | (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-(((2'R,4S,5'R,6aR,6bS,8aS,8bS,9S,11aS,12aS,12bR)-8b-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyra |
| SDF | Download SDF |
| Canonical SMILES | C[C@@H]([C@H](O)[C@@H](O)[C@H]1O)O[C@H]1O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2O[C@@H]3CC4=CC[C@]([C@@](C[C@@]5([H])[C@]6(O)[C@H](C)[C@]7(OC[C@H](C)CC7)O5)([H])[C@]6(C)CC8)([H])[C@@]8([H])[C@@]4(C)CC3 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
