Fatostatin
Catalog No.
A9954
A specific inhibitor of SREBP
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Fatostatin is a specific inhibitor of SREBP (sterol regulatory element binding protein) activation. Fatostatin inhibits the expression of mature and downstream genes by inhibiting the activation of SREBP-1 and SREBP-2 and preventing their transport from the endoplasmic reticulum to the Golgi apparatus. This inhibition results in a reduction in cholesterol and fatty acid synthesis, so Fatostatin is considered to have potential applications in the treatment of metabolic diseases such as obesity and type 2 diabetes. In addition, research suggests that Fatostatin may also have anti-cancer properties.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 294.42 |
| Cas No. | 125256-00-0 |
| Formula | C18H18N2S |
| Solubility | ≥25.35 mg/mL in DMSO; ≥50.6 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | 2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole |
| SDF | Download SDF |
| Canonical SMILES | CCCC1=NC=CC(C2=NC(C3=CC=C(C)C=C3)=CS2)=C1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
