DMG-PEG2000-NHS
Catalog No.
M2004
NHS-PEG derivatives, used for liposomal delivery
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DMG-PEG2000-NHS is a polyethylene glycol (PEG) derivative functionalized with an N-hydroxysuccinimide (NHS) ester. The reactive NHS ester readily forms stable amide linkages upon interaction with primary amine (-NH?) groups, facilitating covalent attachment to peptides, proteins, or amino-functionalized small molecules. Due to these conjugation properties, DMG-PEG2000-NHS is commonly employed in biomedical research for constructing drug delivery platforms such as lipid nanoparticles (LNPs) or liposomes, particularly for siRNA delivery systems.
| Storage | Dry at -20°C. |
| M.Wt | 2000±200 (PEG2000) |
| Solubility | ≥49.7 mg/mL in DMSO; ≥44.7 mg/mL in EtOH; ≥45.3 mg/mL in H2O |
| Chemical Name | 3-(2-(2-((((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)oxy)ethoxy)ethoxy)propane-1,2-diyl ditetradecanoate |
| SDF | Download SDF |
| Canonical SMILES | O=C1CCC(N1OC(OCCOCCOCC(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
