Cy7 azide (non-sulfonated)
Cy7 azide is a labeling reagent that ready for the use in Click Chemistry labeling. This labeling dye is a near-infrared dye which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecules is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. This product can be used for the incorporation of Cy7 azide into various biomolecules and post-synthetic modification of oligonucleotides is also available.
PEG-b-PPLG-Cy7 was conjugated by Cy7 azid and the polymer of PEG-b-PPLG. In blank micelles, it was used to probe the association of unimers [1].
Reference:
[1] Morton, S. W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials,2014, 35(11), 3489-3496.
| Storage | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| M.Wt | 667.33 |
| Formula | C40H51ClN6O |
| Solubility | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Chemical Name | N-(3-azidopropyl)-6-[(2E)-3,3-dimethyl-2-[(2E)-2-[3-[(E)-2-(1,3,3-trimethylindol-1-ium-2-yl)ethenyl]cyclohex-2-en-1-ylidene]ethylidene]indol-1-yl]hexanamide |
| SDF | Download SDF |
| Canonical SMILES | CC1(C2=CC=CC=C2[N+](=C1C=CC3=CC(=CC=C4C(C5=CC=CC=C5N4CCCCCC(=O)NCCCN=[N+]=[N-])(C)C)CCC3)C)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Excitation max (nm) | 750 | Emission max (nm) | 773 |
| Extinction Coefficient (M-1cm-1) | 199000 | Quantum Yield | 0.3 |
| CF260 | 0.022 | CF280 | 0.029 |
Quality Control & MSDS
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Chemical structure
Related Biological Data
