Concanavalin A Magnetic Beads

Concanavalin A (ConA) magnetic beads, made by covalently conjugating the plant lectin ConA (from legume seeds) to superparamagnetic nanospheres, specifically bind α-D-mannose and α-D-glucose residues via carbohydrate recognition domains in a calcium- and manganese-dependent manner. They selectively capture glycoproteins, glycolipids, or polysaccharides from complex biological mixtures for glycobiology research purification/enrichment, serve as targeting probes in CUT&RUN assays for precise genomic profiling, and can be re-used up to five times under recommended conditions without significant activity loss.

Concanavalin A (ConA) is a plant mannose/glucose-binding lectin isolated from the seeds of cereal plants such as giant bean (Jack bean, Canavalia ensiformis), rice, bean, wheat, etc., and its monomer can bind one Ca²⁺ and one Mn²⁺ which Contains a glycosyl-binding site with high affinity for terminal α-D-mannosyl and α-D-glucosyl residues.

Concanavalin A Magnetic Beads (Canoladin A magnetic beads) is covalently coupled with canadolin A and superparamagnetic nanoscale magnetic beads, which can quickly, efficiently, sensitively and specifically bind to glycoproteins, glycolipids, polysaccharides and other glycosylation modification molecules, mainly used to isolate cells or for isolation of cell or tissue lysate or glycoprotein in serum glycosylation modification molecules and other experiments, as well as nuclease-targeted cleavage and release of chromatin (Cleavage Under Targets & Release Using Nuclease, CUT&RUN)。

Table The main related indicators of Concanavalin A Magnetic Beads.