Biotin-16-UTP
Catalog No.
B8154
A biotin-labeled nucleotide analog, used to form labeled RNA
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Biotin-16-UTP is a biotin-labeled uridine triphosphate used for RNA detection and purification. The biotin label allows RNA molecules to bind with streptavidin or anti-biotin proteins, facilitating specific RNA detection and purification. In in vitro transcription reactions, Biotin-16-UTP can be incorporated into RNA molecules, generating biotin-labeled RNA. This labeled RNA has wide applications in RNA-protein interaction studies, RNA detection, and RNA purification. Additionally, biotin-labeled RNA can be applied in in vivo experiments to investigate RNA localization and function within cells.
- 1. Jin Sun, Yingnan Li, et al. "Comprehensive analysis identifies long non-coding RNA RNASEH1-AS1 as a potential prognostic biomarker and oncogenic target in hepatocellular carcinoma." Am J Cancer Res. 2024 Mar 15;14(3):996-1014. PMID: 38590422
- 2. Mengya Guo, Hao Zhuang, et al. "LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progression." Mol Cell Biochem. 2022 Dec 30. PMID: 36583796
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 963.8 (free acid) |
| Formula | C32H52N7O19P3S (free acid) |
| Synonyms | Biotin-16-Aminoallyluridine-5'-Triphosphate, Biotin-16-UTP |
| Chemical Name | lithium (E)-(5-(2,4-dioxo-5-(3-(4-(6-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)butanamido)prop-1-en-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | O=C(C(/C=C/CNC(CCCNC(CCCCCNC(CCCCC1C(NC(N2)=O)C2CS1)=O)=O)=O)=CN3C4C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O4)NC3=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = ≥90% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
