Biotin-16-UTP
Catalog No.
B8154
A biotin-labeled nucleotide analog, used to form labeled RNA
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Biotin-16-UTP is a biotin-labeled uridine triphosphate used for RNA detection and purification. The biotin label allows RNA molecules to bind with streptavidin or anti-biotin proteins, facilitating specific RNA detection and purification. In in vitro transcription reactions, Biotin-16-UTP can be incorporated into RNA molecules, generating biotin-labeled RNA. This labeled RNA has wide applications in RNA-protein interaction studies, RNA detection, and RNA purification. Additionally, biotin-labeled RNA can be applied in in vivo experiments to investigate RNA localization and function within cells.
- 1. Mingfeng Xie, Huan He, et al. "In Situ Spatiotemporal Tracking of Endogenous Protein Dynamics with Allosteric Genetically Encoded Biosensor in Living Cells." Biosensors and Bioelectronics Volume 310, 15 October 2026, 118829
- 2. Andreas Martinez, Nelson Ruth, et al. "Aerosol biome of a cafeteria and medical facility in Los Alamos, New Mexico, USA." Environmental Microbiology 10 September 2025
- 3. Jin Sun, Yingnan Li, et al. "Comprehensive analysis identifies long non-coding RNA RNASEH1-AS1 as a potential prognostic biomarker and oncogenic target in hepatocellular carcinoma." Am J Cancer Res. 2024 Mar 15;14(3):996-1014. PMID: 38590422
- 4. Mengya Guo, Hao Zhuang, et al. "LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progression." Mol Cell Biochem. 2022 Dec 30. PMID: 36583796
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 963.8 (free acid) |
| Formula | C32H52N7O19P3S (free acid) |
| Synonyms | Biotin-16-Aminoallyluridine-5'-Triphosphate, Biotin-16-UTP |
| Chemical Name | lithium (E)-(5-(2,4-dioxo-5-(3-(4-(6-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)butanamido)prop-1-en-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate |
| Canonical SMILES | O=C(C(/C=C/CNC(CCCNC(CCCCCNC(CCCCC1C(NC(N2)=O)C2CS1)=O)=O)=O)=CN3C4C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O4)NC3=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = ≥90% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
