5-hme-UTP
Catalog No.
B8054
Uridine triphosphate containing 5-hydroxymethyl modification, enhancing RNA stability
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5-hme-UTP (5-hydroxymethyluridine triphosphate) is a modified uridine triphosphate with a hydroxymethyl group attached at the 5-carbon position. This modification can enhance RNA stability and functionality. During in vitro mRNA synthesis, 5-hme-UTP can be incorporated into RNA molecules to generate RNA containing 5-hydroxymethyluridine. RNAs modified with hydroxymethyl groups play an important role in studies of RNA structure, function, and interactions with proteins. Additionally, 5-hme-UTP significantly increases RNA stability and reduces degradation within cells. Thus, this modification has broad applications in gene expression research, RNA therapeutic development, and gene therapy.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 514.7 |
| Formula | C10H17N2O16P3 (free acid) |
| Synonyms | 5-Hydroxymethyluridine-5’-Triphosphate, 5-hm-UTP, 5-Hydroxymethyl-UTP, 5-HmUTP |
| Chemical Name | lithium (3,4-dihydroxy-5-(5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | O=C(C(CO)=CN1C2C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)NC1=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.60% by AX-HPLC
- COA (Certificate Of Analysis)
- HPLC
- MSDS (Material Safety Data Sheet)
Chemical structure
