Tiliroside
Catalog No.
N2081
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Tiliroside (CAS 20316-62-5) is a naturally-derived flavonoid classified as a glycosylated flavonoid. It is reported to modulate multiple cellular pathways, thereby influencing antioxidant defense, inflammatory signaling, and metabolic enzyme activity.
Tiliroside exerts its biological activity primarily through antioxidant, anti-inflammatory, and enzyme-inhibitory mechanisms.
Tiliroside holds research potential in studies investigating oxidative stress responses, inflammatory signal pathways, metabolic enzyme regulation, and related molecular processes.
- 1. Fangfang Cai , Kaiqian Zhou, et al. "A novel KEAP1 inhibitor, tiliroside, activates NRF2 to protect against acetaminophen-induced oxidative stress and acute liver injury." Hepatol Commun.2025 Feb 26;9(3):e0658. PMID: 40008899
- 2. Fangfang Cai, Dangran Li, et al. "Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction." Phytomedicine. 2024 Apr:126:155407. PMID: 38340577
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 594.52 |
| Cas No. | 20316-62-5 |
| Formula | C30H26O13 |
| Solubility | ≥59.5 mg/mL in DMSO; insoluble in H2O; ≥2.67 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | [(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate |
| SDF | Download SDF |
| Canonical SMILES | OC1=CC(O)=C(C(C(O[C@H]2O[C@H](COC(/C=C/C3=CC=C(O)C=C3)=O)[C@@H](O)[C@H](O)[C@H]2O)=C(C4=CC=C(O)C=C4)O5)=O)C5=C1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
