Nootkatone
Nootkatone (CAS4674-50-4) is a naturally derived agent investigated for its neuroprotective effects. It is designed to modulate intracellular signaling pathways and enzymatic activities associated with neuroinflammation and oxidative stress, thereby regulating neuronal cellular processes.
Nootkatone exerts its biological activity primarily through modulation of signaling pathways and enzymatic activities linked to neuroinflammation and oxidative stress. In animal models, specifically lipopolysaccharide (LPS)-induced Alzheimer's disease in mice, Nootkatone demonstrates amelioration of cognitive impairment.
Nootkatone holds research potential in neuronal protection, cognitive function restoration, and elucidation of mechanisms related to neurodegenerative pathology.
| Storage | Store at -20°C |
| M.Wt | 218.33 |
| Cas No. | 4674-50-4 |
| Formula | C15H22O |
| Synonyms | (+)-Nootkatone |
| Solubility | ≥41.2 mg/mL in DMSO; ≥37.3 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (4R,4aS,6R)-4,4a-dimethyl-6-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one |
| SDF | Download SDF |
| Canonical SMILES | C[C@H](C1)[C@](C)(C[C@@H](CC2)C(C)=C)C2=CC1=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
