Search results for: 'signaling pathways membrane transporter ion channel cftr AND select 5033'
- Danoprevir (RG7227)Catalog No. :A4024HCV NS3/4A protease inhibitorDanoprevir (R7227) is a potent and selective inhibitor of Hepatitis C Virus (HCV) NS3/4A protease, a chymotrypsin-like serine protease playing an essential role in the viral replication process of HCV, that non-covalently binds to and hence inhibits HCV NS3 protease with 50% inhibition concentration IC50 values ranging from 0.2 to 3.5 nM.
- PSI-6206Catalog No. :A8189Inhibitor of HCV RNA polymerase,potent and selectivePSI-6206 (as known as RO-2433 or GS-331007), β-D-2’-deoxy-2’-fluoro-2’-C-methyluridine, is the deaminated derivative of PSI-6130, β-D-2’-deoxy-2’-fluoro-2’-C-methylcytidine, which is a potent inhibitor of hepatitis C virus (HCV) replication in the subgenomic HCV reolicon system.
- Daclatasvir (BMS-790052)Catalog No. :A5618HCV NS5A inhibitorDaclatasvir, formerly known as BMS-790052, is a potent NS5A inhibitor with EC50 values varying from 9 to 146 pM.