Penicillin-Streptomycin-Amphotericin B Solution (100×)

Penicillin-Streptomycin-Amphotericin B Solution (100×) is a sterile, ready-to-use triple antibiotic cocktail designed for prevention of bacterial contamination in cell culture. The solution is filter-sterilized and can be directly added to cell culture medium. In addition to standard antibacterial agents, this formulation contains the antifungal agent Amphotericin B. It provides broad-spectrum protection against bacterial, fungal, and yeast contamination.

This formulation is based on our Penicillin-Streptomycin Solution (100×) (Cat# K2803), with the addition of amphotericin B. Penicillin is a β-lactam antibiotic that inhibits bacterial cell wall synthesis. Streptomycin is an aminoglycoside antibiotic that act by inhibiting bacterial protein synthesis. Amphotericin B is a polyene antifungal agent that effectively suppresses fungal and yeast contamination.

This product is formulated in 0.9% NaCl and contains 10,000 units/mL penicillin, 10 mg/mL streptomycin and 25 μg/mL amphotericin B. It is generally used in a 100X dilution. 100 mL of this solution is sufficient to prepare 10 L of complete growth medium.