Levomefolic acid
Catalog No.
C8650
Levomefolic acid (L-5-MTHF) is a natural, orally bioavailable, brain-penetrant active form of folic acid. It is one of the most widely used folic acid supplements for supporting folate metabolism and neurological health.
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Levomefolic acid (CAS: 31690-09-2), also known as L-5-methyltetrahydrofolate (L-5-MTHF), is the biologically active form of folic acid found naturally in the body. Unlike synthetic folic acid, it bypasses the need for dihydrofolate reductase conversion, offering superior bioavailability and direct physiological activity. Levomefolic acid effectively crosses the blood-brain barrier, making it a valuable supplement in the management of folate deficiency, methylation disorders, pregnancy support, and neurological health. It is especially beneficial for individuals with impaired folate metabolism or MTHFR polymorphisms.
| Storage | Store at -20°C and below away from light for 3 years. |
| M.Wt | 459.46 |
| Cas No. | 31690-09-2 |
| Formula | C20H25N7O6 |
| Synonyms | L-5-MTHF |
| Solubility | ≥5.45 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O |
| Chemical Name | (4-((((S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid |
| SDF | Download SDF |
| Canonical SMILES | O=C(N[C@@H](CCC(O)=O)C(O)=O)C1=CC=C(NC[C@H](N2C)CNC3=C2C(N=C(N)N3)=O)C=C1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 95.85%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
