Hyoscyamine
Catalog No.
B1605
AChR inhibitor
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Hyoscyamine (CAS 101-31-5) is a small molecule antagonist targeting acetylcholine receptors (AChR). Acting via inhibition of cholinergic signaling, it exhibits a potent inhibitory activity with an IC50 of approximately 7.5 nM. By blocking AChRs, hyoscyamine modulates neurotransmission pathways involved in autonomic regulation. Research applications include studies exploring cholinergic function, investigations into parasympathetic nervous system disorders, and testing therapeutic strategies involving ACh modulation.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 289.37 |
| Cas No. | 101-31-5 |
| Formula | C17H23NO3 |
| Solubility | ≥14.47 mg/mL in DMSO; ≥2.58 mg/mL in H2O with gentle warming and ultrasonic; ≥60.2 mg/mL in EtOH |
| Chemical Name | [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate |
| SDF | Download SDF |
| Canonical SMILES | O=C([C@@H](CO)C1=CC=CC=C1)O[C@H]2C[C@@H]3N(C)[C@H](C2)CC3 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
