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DNase I (GMP-grade)

Catalog No.
K1088R
An endonuclease that can digest single- or double-stranded DNA
Grouped product items
SizePriceStock Qty
50KU
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Please inquire
500KU
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2500KU
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Please inquire
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Description

DNase I is a deoxyribonucleic acid endonuclease that hydrolyzes single- or double-stranded DNA, producing dinucleotide, trinucleotide, and oligonucleotide products with 3’-hydroxyl and 5’-phosphate group ends. The activity of DNase I is Ca2+ dependent and can be activated by either Mg2+ or Mn2+. In the presence of Mg2+, DNase I can randomly cleave any site of double-stranded DNA. In the presence of Mn2+, DNase I recognizes both strands of DNA simultaneously and cleaves them at nearly identical sites.

DNase I can act on single-stranded DNA, double-stranded DNA, chromatin, and RNA:DNA hybrids. It is suitable for RNA extraction, in vitro transcription, and DNA removal in RT-PCR experiments. The production process of this product strictly controls host protein residues, nucleic acid residues, etc., and conforms to GMP production and quality management standards.

Quality Control

Quality Control & DataSheet

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Components and Storage

Components

50 KU

500 KU

2500 KU

Storage

DNase I (50 KU/mL)

1 mL

10 mL

50 mL

-70°C or below

Shipping: Dry Ice                                 Shelf life: 2 years