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BIBP 3226 trifluoroacetate

Catalog No.
B7155
Mixed NPY Y1 and NPFF receptor antagonist
Grouped product items
SizePriceStock Qty
2mg
$460.00
In stock
10mg
$508.00
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For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

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Background

BIBP 3226 trifluoroacetate (CAS: 1068148-47-9) is a non-peptide antagonist targeting neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptors, showing binding affinity with Ki values of 1.1 nM (rNPY Y1), 79 nM (hNPFF2), and 108 nM (rNPFF). BIBP 3226 competes with NPFF, prevents NPFF-induced inhibition of forskolin-stimulated cAMP production, and blocks NPFF-dependent hypothermic and anti-opioid effects in rodent models. This compound is employed experimentally to investigate NPY/NPFF system roles in anxiety, analgesia, and cardiovascular regulation.

Chemical Properties

Physical AppearanceOff-white solid
StorageStore at -20°C
M.Wt587.59
Cas No.1068148-47-9
FormulaC29H32F3N5O5
Solubility≥78 mg/mL in DMSO; ≥73.2 mg/mL in EtOH; ≥12.13 mg/mL in H2O with ultrasonic
Chemical Namerac-(R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-hydroxybenzyl)pentanamide 2,2,2-trifluoroacetate
SDFDownload SDF
Canonical SMILESFC(F)(C(O)=O)F.OC1=CC=C(C=C1)CNC([C@@H](CCCNC(N)=N)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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