Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Catalog No.
MA4463
Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
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An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
2475
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
Rabbit
Human, Mouse
Unconjugated
Calculated MW: 289 kDa; Observed MW: 289 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-18D11H6
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.