Vitamin D3
Catalog No.
B2065
Fat-soluble secosteroids
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Vitamin D3 (Cholecalciferol, CAS 67-97-0) is an endogenous fat-soluble vitamin that serves as a precursor requiring metabolic conversion to its biologically active metabolite. Following hydroxylation, the active form exerts its function predominantly by binding the nuclear vitamin D receptor (VDR), modulating gene expression pathways involved in cellular differentiation and proliferation. Research indicates that activated Cholecalciferol promotes cellular differentiation and exhibits anti-proliferative effects against various cancer cell types. Consequently, Vitamin D3 is frequently utilized in biomedical research studying mechanisms underlying tumor development and differentiation pathways.
- 1. Yongdeok Jo, Ujjayan Majumdar, et al. "Vitamin D3 Release from MgO Doped 3D Printed TCP Scaffolds for Bone Regeneration." ACS Biomater Sci Eng. 2024 Mar 11;10(3):1676-1685. PMID: 38386843
- 2. Kang Rong, Qingmin He, et al. "The mechanism of vitamin D3 in preventing colorectal cancer through network pharmacology." Front Pharmacol. 2023 May 17:14:1192210. PMID: 37266156
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 384.64 |
| Cas No. | 67-97-0 |
| Formula | C27H44O |
| Solubility | insoluble in H2O; ≥51.6 mg/mL in DMSO; ≥77.2 mg/mL in EtOH |
| Chemical Name | (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol |
| SDF | Download SDF |
| Canonical SMILES | CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
