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MK-4827 hydrochloride

Catalog No.
B1163
PARP1/PARP2 inhibitor
Grouped product items
SizePriceStock Qty
5mg
$77.00
In stock
10mg
$110.00
In stock
50mg
$198.00
In stock
100mg
$308.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

MK-4827(Niraparib) Hcl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.

Chemical Properties

StorageStore at -20°C
M.Wt356.85
Cas No.1038915-64-8
FormulaC19H21ClN4O
Solubility≥23.7 mg/mL in DMSO; ≥20.85 mg/mL in EtOH; ≥41.7 mg/mL in H2O
Chemical Name2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide;hydrochloride
SDFDownload SDF
Canonical SMILESNC(c1cccc2c[n](-c3ccc([C@H]4CNCCC4)cc3)nc12)=O.Cl
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control