MDL 100907
Catalog No.
B7605
5-HT2A receptor antagonist
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MDL 100907 (CAS 139290-65-6), also known as volinanserin, is a selective antagonist at the serotonin (5-HT) receptor subtype 5-HT2A. Through inhibition of 5-HT2A signaling, the compound modulates serotonergic neural pathways implicated in central nervous system regulation. Its pharmacological profile has led to investigation in clinical research, notably evaluating therapeutic potential in sleep maintenance insomnia, as reflected in polysomnographic clinical trials assessing sleep parameters and safety outcomes.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 373.46 |
| Cas No. | 139290-65-6 |
| Formula | C22H28FNO3 |
| Solubility | ≥122.2 mg/mL in DMSO; ≥90.8 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (S)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol |
| SDF | Download SDF |
| Canonical SMILES | FC1=CC=C(C=C1)CCN2CCC([C@@H](C3=CC=CC(OC)=C3OC)O)CC2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
