LL 37
Catalog No.
B7771
Antimicrobial peptide derivative of human cathelicidin
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LL-37 (CAS 154947-66-7) is a naturally occurring antimicrobial peptide derived from human cathelicidin, consisting of 37 amino acids with amphipathic structure. Its mechanism involves interaction with bacterial membranes, resulting in membrane disruption and broad-spectrum antibacterial activity. In addition to its antimicrobial role, LL-37 modulates immune response, contributes to inflammatory regulation, and participates in wound healing through influencing cell migration and proliferation. Current biomedical research employs LL-37 for investigating infection control, immune modulation pathways, and tissue repair processes.
- 1. Qiushi Zheng, Chao Li, et al. "Candida auris cells form giant lipid droplets to survive in harsh environments." Commun Biol. 2025 May 22;8(1):783. PMID: 40404799
- 2. Jian Bing, Zhangyue Guan, et al. "Rapid evolution of an adaptive multicellular morphology of Candida auris during systemic infection." Nat Commun. 2024 Mar 16;15(1):2381. PMID: 38493178
| Physical Appearance | White lyophilised solid |
| Storage | Store at -20°C |
| M.Wt | 4493.32 |
| Cas No. | 154947-66-7 |
| Formula | C205H340N60O53 |
| Solubility | Soluble in H2O |
| SDF | Download SDF |
| Canonical SMILES | CC[C@]([C@@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/[C@](N)([H])CC(C)C)([H])CC(C)C)([H])CC(O)=O)([H])CC1=CC=CC=C1)([H])CC2=CC=CC=C2)([H])CCCNC(N)=N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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