GABAA receptor potentiator
Etifoxine is potentiator of GABAA receptor function in cultured neurons. Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration.
|Physical Appearance||A solid|
|Storage||Store at -20°C|
|Solubility||≥33.7 mg/mL in DMSO with gentle warming, ≥48.1 mg/mL in EtOH with gentle warming, ≥15.49 mg/mL in H2O with gentle warming|
|Shipping Condition||Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|