Dxd
Catalog No.
BA2320
Dxd (ExatecanderivativeforADC) is a potent inhibitor.
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Dxd (ExatecanderivativeforADC) is a potent inhibitor with a value of 0.31 μM that can be used as a payload for the antibody-coupled drug ADC (DS-8201a) targeting HER2.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 493.48 |
| Cas No. | 1599440-33-1 |
| Formula | C26H24FN3O6 |
| Synonyms | Exatecanderivative for ADC |
| Solubility | ≥54.1 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| Chemical Name | N-((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)-2-hydroxyacetamide |
| SDF | Download SDF |
| Canonical SMILES | O=C(CO)N[C@H]1CCC2=C3C(N=C4C(N5CC4=C31)=CC6=C(COC([C@]6(O)CC)=O)C5=O)=CC(F)=C2C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
