Docosapentaenoic Acid

Docosapentaenoic Acid (CAS No.: 24880-45-3) is a long-chain omega-3 polyunsaturated fatty acid that is widely distributed in animal cell phospholipid membranes and is also present in fish oils, where it contributes to the pool of circulating unsaturated fatty acids in humans. As an integral component of membrane lipids, it plays a critical role in regulating membrane fluidity, lipid raft organization, and signal transduction processes, thereby influencing cellular metabolism, inflammatory responses, and disease-related pathways. Mechanistically, it has been associated with modulation of inflammatory signaling cascades and metabolic enzyme activity, including inhibitory effects on carbohydrate-hydrolyzing enzymes such as α-amylase and α-glucosidase, with reported activity in the low micromolar range, as well as modest enhancement of cell viability and weak anti-inflammatory properties. These features position docosapentaenoic acid as a useful tool compound for investigating lipid-mediated regulation of cellular signaling, metabolic homeostasis, and inflammation, particularly in the context of cardiovascular and neurological disease research. In experimental settings, it is commonly applied in cell-based assays and in vivo models to study lipid metabolism and membrane biology, with concentrations or dosing regimens adjusted according to specific experimental designs and research objectives.