Zymosan A

Zymosan A (CAS 58856-93-2) is a polysaccharide compound extracted from yeast cell walls, mainly derived from Saccharomyces cerevisiae. Zymosan A activates the immune system, particularly by binding to pattern recognition receptors (such as Toll-like receptor 2 and Dectin-1) to induce immune cells to produce cytokines and other inflammatory mediators. Zymosan A is therefore commonly used to study innate immune responses and inflammatory mechanisms and to evaluate the efficacy of anti-inflammatory drugs.

Zymosan A is commonly used to establish systemic inflammation (peritonitis) animal models; intraperitoneal administration induces inflammatory exudation and multi-organ injury, and it is widely used for anti-inflammatory drug evaluation.