Vancomycin
Catalog No.
C6417
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Vancomycin (CAS 1404-90-6) is a glycopeptide antibiotic originally isolated from Streptomyces orientalis. It exerts antibacterial activity primarily by inhibiting bacterial cell wall synthesis through binding to D-Ala-D-Ala termini of peptidoglycan precursors, thereby preventing proper polymerization and cross-linking. Vancomycin serves as an important tool in biomedical research studying bacterial resistance mechanisms and is clinically employed in managing conditions such as Clostridium difficile-associated diarrhea and enterocolitis due to methicillin-resistant Staphylococcus aureus.
- 1. Shuiping Yan, Jian Zheng, et al. "Effect of Shufeng xingbi Therapy on Th1/Th2 immune balance and intestinal flora in rats with allergic rhinitis." bioRxiv. March 29, 2025.
- 2. Fuqiang Ma, Weiming Zhang, et al. "Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis." Int Immunopharmacol. 2024 Aug 20:137:112472. PMID: 38897131
| Storage | Store at -20°C |
| M.Wt | 1449.25 |
| Cas No. | 1404-90-6 |
| Formula | C66H75Cl2N9O24 |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥97.2 mg/mL in DMSO |
| SDF | Download SDF |
| Canonical SMILES | O[C@@H]1[C@H](C)O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC3=C(OC4=C(Cl)C=C([C@@H](O)[C@@H](NC([C@H](NC)CC(C)C)=O)C(N[C@@H](CC(N)=O)C5=O)=O)C=C4)C=C([C@@](C(N[C@@H]6C7=CC8=C(O)C=C7)=O)([H])N5)C=C3OC(C=C9)=C(Cl)C=C9[C@@H](O)[C@@H](C(N[C@H](C(O)=O) |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
