PLX-5622
Catalog No.
B8575
An orally available selective CSF1R (Colony stimulating factor 1 receptor) inhibitor.
Featured Products
PLX-5622 is an orally available selective CSF1R (Colony stimulating factor 1 receptor) inhibitor. CSF1R is expressed in a variety of cell types, especially in microglia and macrophages, and is involved in regulating the growth, differentiation, and survival of these cells. By inhibiting CSF1R, PLX-5622 can effectively reduce the number of microglia and macrophages, which has important applications in the study of neuroinflammation and neurodegenerative diseases.
| Physical Appearance | Solid |
| Storage | Store at -20°C for 3 years. |
| M.Wt | 395.41 |
| Cas No. | 1303420-67-8 |
| Formula | C21H19F2N5O |
| Synonyms | PLX5622 |
| Solubility | ≥41.6 mg/mL in DMSO; ≥3.08 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | 6-fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine |
| SDF | Download SDF |
| Canonical SMILES | Cc1cc(c(Cc2ccc(NCc(cc(cn3)F)c3OC)nc2F)c[nH]2)c2nc1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
